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DNA polymerases

Found 9 search result(s) for "DNA polymerase".

Page: 2.4 Robert Gallo — Discoveries of Human Retrovirus, Their Linkage to Disease as Causative Agents & Preparation for the Future (HIV/AIDS Research: Its History & Future Meeting)
... 5) That's what Robin referenced last night, in which we showed that this was DNA polymerase gamma associated with mitochondria, the RNA was a primer. It was directed by DNA. It's mitochondrial DNA synthesis. That's what the Simultaneous Detection assay was picking up, so ...
Apr 27, 2021
Page: 1.5 John Coffin — The Origin of Molecular Retrovirology (HIV/AIDS Research: Its History & Future Meeting)
... 6. Nature 226, June 27, 1970: Baltimore, David. “Viral RNADependent DNA Polymerase: RNADependent DNA Polymerase in Virions of RNA Tumour Viruses.” Nature 226, no. 5252 (June 27, 1970 ... ...
Apr 27, 2021
Page: 2.5 Françoise Barré-Sinoussi — Discovery of HIV (HIV/AIDS Research: Its History & Future Meeting)
... looking by reverse transcriptase assays to try to differentiate between 00:08:30 DNA polymerase and reverse transcriptase activities in the cell supernatants.  #lab vs. clinic #early theories ... possible. We did it. We did it by making a small probe in order to clean the  ...
Apr 27, 2021
Page: 1.4 Robin Weiss — Retrovirus History and Early Searches for Human Retroviruses (HIV/AIDS Research: Its History & Future Meeting)
... 00426822(70)904289 https://doi.org/10.1016/00426822(70)904289. Baltimore, David. “Viral RNADependent DNA Polymerase: RNADependent DNA Polymerase in Virions of RNA Tumour Viruses.” Nature 226, no. 5252 (June 27, 1970 ... ...
Apr 27, 2021
Page: 3.1 Marty St. Clair: Discovery of AZT as the First Anti-HIV Drug (HIV/AIDS Research: Its History & Future Meeting)
... development program with acyclovir, which, once phosphorylated, inhibits herpes simplex virus DNA polymerase. We believed we would be successful in HIV doing exactly the same thing ... We didn't know it was caused by a retrovirus. As you all know, retrovirus doublestranded ...
Apr 27, 2021
Page: 8.3 George Shaw — Transmitted/Founder HIV Genomes: What They Teach Us (HIV/AIDS Research: Its History & Future Meeting)
... Geoffrey M. https://libwiki.cshl.edu/confluence/pages/viewpage.action?pageId=15534898 credit, priority https://libwiki.cshl.edu/confluence/display/AT/credit%2Cpriority cytokines cytomegalovirus (CMV) https://libwiki.cshl.edu/confluence/pages/viewpage.action?pageId=12944757 DNA polymerase https://libwiki.cshl.edu/confluence/display/AT/DNApolymerase education and early career https://libwiki.cshl.edu/confluence/display/AT/educationandearlycareer ELISpot (enzymelinked immune absorbent spot ... ...
Apr 27, 2021
Page: 3.5 Daria Hazuda: Discovery and Development of Integrase Inhibitors (HIV/AIDS Research: Its History & Future Meeting)
... against Human Immunodeficiency Virus Type 1, Intracellular Metabolism, and Effects on Human DNA Polymerases of 4′Ethynyl2Fluoro2′Deoxyadenosine.” Antimicrobial Agents and Chemotherapy 51, no. 8 (August 1 ... blocking a critical step in the viral life cycle, the insertion of the fully reversetranscribed viral ...
Apr 27, 2021
Page: 1.6 Harold Varmus — Animal Retroviruses and Cancer Research (HIV/AIDS Research: Its History & Future Meeting)
... Jana Hillová, and Jan Svoboda (1934–2017, Czech virologist) carried out DNA transformation studies showing that some form of the viral genome, presumably DNA, was in cells, but they didn't rigorously prove that it was linked to host chromosomes. (2) There was molecular hybridization ...
Apr 27, 2021
Page: 3.6 John C. Martin — Making it Simpler: A Single Pill to Treat HIV (HIV/AIDS Research: Its History & Future Meeting)
... molecules and that methyl group is the one position that allows—that reduces the affinity of this for human mitochondrial DNA polymerase. That methyl group, although a very simple modification, really changed the future. The study ... ...
Apr 27, 2021

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