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A technique to detect and analyze RNA in gel electrophoresis, developed in 1977. The name "Northern blot" is used by analogy to the "Southern blot," invented in 1975 and the original of the "blot" techniques used to analyze DNA in gels. The later "Western blot" is used to analyze denatured proteins.

Found 3 search result(s) for "Northern blot".

Page: Western blot (HIV/AIDS Research: Its History & Future Meeting)
... electrophoresis, using an animal antibody to target a denatured protein. Invented in 1979. A Southern blot (named after Edwin Southern) is used to detect and analyze DNA, while a Northern ...
Jan 03, 2021
Page: 5.1 Flossie Wong-Staal — Discovery of Human Retroviral Transactivators (HIV/AIDS Research: Its History & Future Meeting)
... may hit a gene that is separate from tat. If you look at the expression pattern by Northern blot 00:15:00 in wild type infected cells, you see three ...
Apr 27, 2021
Page: 5.3 Michael Malim — Discovery of APOBEC Restriction (HIV/AIDS Research: Its History & Future Meeting)
... cDNA subtraction to identify cDNA selectively expressed in nonpermissive cells, screening them by Northern blotting to see which ones gave the right 00:07:00 expression profile ...
Apr 27, 2021

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