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focus assay for Rous sarcoma virus: developed by Howard Temin and Harry Rubin in 1958, the focus assay permitted quantitative study of RSV in a petri dish, rather than in adult chicken tumors or chicken embryos.

Howard M. Temin and Harry Rubin, “Characteristics of an Assay for Rous Sarcoma Virus and Rous Sarcoma Cells in Tissue Culture,” Virology 6, no. 3 (December 1958): 669–88, doi:10.1016/0042-6822(58)90114-4.

Found 2 search result(s) for "focus assay".

Page: 1.4 Robin Weiss — Retrovirus History and Early Searches for Human Retroviruses (HIV/AIDS Research: Its History & Future Meeting)
... Iron Curtain At the bottom of the slide 00:06:30 is an example of this cell transformation assay or focus assay for Rous sarcoma virus that Howard Temin and Harry Rubin developed at Caltech while ... way of titrating them, as well as a way of examining what's going on in cell transformation. # ...
Apr 27, 2021
Page: 1.5 John Coffin — The Origin of Molecular Retrovirology (HIV/AIDS Research: Its History & Future Meeting)
... biologist and virologist). Harry was a terrific biologist. They developed this, as was pointed out in the previous talk, the focus assay for Rous sarcoma virus. (1) This was the first 00:06:00 quantitative assay ... ...
Apr 27, 2021

 

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