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Limiting dilution analysis, or limiting dilution assay, or dilution cloning. An older technique of obtaining a monoclonal cell culture from a heterogenous population of cells by setting up a series of dilutions from cell suspensions.

Found 2 search result(s) for "limiting dilution".

Page: 8.2 David Ho — Unraveling of HIV Dynamics In Vivo (HIV/AIDS Research: Its History & Future Meeting)
... did a systematic evaluation of trying to quantify HIV in blood. This we did by the oldfashioned limiting dilution culture technique. (1) To our surprise, we found that in a lot of cases, a few ...
Apr 27, 2021
Page: 8.4 Robert Siliciano — The Challenge of the HIV Reservoir (HIV/AIDS Research: Its History & Future Meeting)
... definitive assay for this reservoir. In this assay, you take resting cells, plate them in limiting dilution, and then activate them under conditions where 100% of the cells undergo blast transformation ...
Apr 27, 2021

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