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Monoclonal antibodies are antibodies that are made by identical immune cells, which are all clones belonging to a unique parent cell. They can be produced industrially in culture, or using genetically modified yeast by cloning immunoglobulin gene segments.

Found 14 search result(s) for monoclonal antibody.

Page: 6.2 Dennis Burton — How Does HIV Evade the Antibody Response? (HIV/AIDS Research: Its History & Future Meeting)
... speaking, not that much probably. That's where the strategy is always look to induce multiple antibodies. And polyclonal—we're not trying to induce monoclonals, we're trying to induce a series of antibodies that look like 00:33:30 that monoclone plus a whole thing repeated ...
Apr 27, 2021
Page: 4.0.2 Ruth Ruprecht — Session 4, Introduction 2 (HIV/AIDS Research: Its History & Future Meeting)
... Video http://library.cshl.edu/Meetings/HIVAIDS/videopages/Ruprecht.php Index 4.0.1 Jeffrey Lifson — Session 4, Introduction 1 antibody, immunoglobulin (Ig) env HIV vaccine macaque, rhesus macaque monoclonal antibody prevention of HIV/AIDS simian immunodeficiency virus (SIV) simianhuman immunodeficiency virus ...
Apr 27, 2021
Page: 4.1 Ronald Desrosiers — The Origin of SIVmac: Non-human Primate Models for HIV (HIV/AIDS Research: Its History & Future Meeting)
... come in one day, one arm, AAV one—AAV making one monoclonal antibody, AAV making a second monoclonal antibody. You deliver therapeutic levels. They go off antiviral drugs and they continued to be suppressed ... ...
Apr 27, 2021
Page: 6.4 Barton Haynes — Development of HIV Vaccine: Steps and Missteps (HIV/AIDS Research: Its History & Future Meeting)
... about. (10) You do what Dennis talked about. You isolate the monoclonal antibodies from a broadly neutralizing antibodyproducing individual. Then, through computational techniques or by actually isolating ... diagnosed as 00:27:30 lupus and one of the diagnostic criterias was doublestranded DNA antibody ...
Apr 27, 2021
Page: 8.6 David Baltimore — Bringing it to an End (And Where Are We Going?) (HIV/AIDS Research: Its History & Future Meeting)
... we really want it to do and we know about that well enough, and that is to make monoclonal antibodies—to make antibodies of the quality of the monoclonal antibodies that are so effective in breadth and potency that have been 00:13:30 found ... ...
Apr 27, 2021
Page: Bureau of Biologics (FDA) (HIV/AIDS Research: Its History & Future Meeting)
... Center for Drug Evaluation and Research (CDER) has jurisdiction over proteinbased therapies such as monoclonal antibodies
Mar 07, 2021
Page: Session 7: Prospects for an HIV Vaccine (HIV/AIDS Research: Its History & Future Meeting)
... patients, I began to think that what was important was 00:11:00 to look at the antibodies that the patients were making. We started making human monoclonal antibodies. This is in the mid1980s, and believe me, it was not easy to make human monoclonal antibodies in the mid1980s. We were ...
Apr 27, 2021
Page: 6.5 Emilio Emini — Issues in HIV Vaccine Development: Will the Future be any Easier than the Past? (HIV/AIDS Research: Its History & Future Meeting)
... one of the new tools which had just become available in those days was monoclonal antibodies, mousederived monoclonal antibodies. I spent essentially three years of my postdoc trying to understand the nature ... ...
Apr 27, 2021
Page: 8.3 George Shaw — Transmitted/Founder HIV Genomes: What They Teach Us (HIV/AIDS Research: Its History & Future Meeting)
... two Cell papers (17, 18) all on this one subject, characterizing the types of monoclonal antibodies that developed in the humans, and the antibody specificities of the neuts that led to the development and neutralization breadth.  There was one set of antibodies called CH235 and CH103, that each are broadly neutralizing monoclonals ...
Apr 27, 2021
Page: 5.1 Flossie Wong-Staal — Discovery of Human Retroviral Transactivators (HIV/AIDS Research: Its History & Future Meeting)
... response to kill the virusinfected cells.  The molecule I'm going to talk about is developed, is an antibody, a humanized monoclonal antibody against CD4. It's an antibody developed at UBI, United Biomedical Inc. which is headquartered 00:24:30 ...
Apr 27, 2021
Page: 2.5 Françoise Barré-Sinoussi — Discovery of HIV (HIV/AIDS Research: Its History & Future Meeting)
... knowledge both in retrovirology and also, as it was said by Jeff Lifson before, in immunology with the development of monoclonal antibody with the development also of the identification of growth factor like IL2.  So instead of looking ... p15 (p19)  and another patient that was 00:11:30 with AIDS, was capable to have ...
Apr 27, 2021
Page: 1.4 Robin Weiss — Retrovirus History and Early Searches for Human Retroviruses (HIV/AIDS Research: Its History & Future Meeting)
... Weekly Report https://libwiki.cshl.edu/confluence/display/AT/MMWRMorbidityandMortalityWeeklyReport models (model systems, model organisms, modeling) https://libwiki.cshl.edu/confluence/pages/viewpage.action?pageId=12944094 monoclonal antibody https://libwiki.cshl.edu/confluence/display/AT/monoclonalantibody monocyte https://libwiki.cshl.edu/confluence/display/AT/monocyte Montagnier, Luc (b. 1932) https://libwiki.cshl.edu/confluence/pages/viewpage.action?pageId=12943777 Mulago National ... ...
Apr 27, 2021
Page: 2.4 Robert Gallo — Discoveries of Human Retrovirus, Their Linkage to Disease as Causative Agents & Preparation for the Future (HIV/AIDS Research: Its History & Future Meeting)
... retroviruses, now we're going to have another whole category. That thing was crossreacting with monoclonal antibodies to HTLV1, yet it was different, it was cytopathic, it had other differences. It really held us ... doubleblind study, and 100% of AIDS sera scored positive. Somebody asked about  ...
Apr 27, 2021
Page: 2.1 Paul Volberding — The First Patients (HIV/AIDS Research: Its History & Future Meeting)
... time when Ed and his colleagues had just described some of the first monoclonal antibodies, at that time a relatively new technology, that differentiated human T cell subsets. I ... ...
Apr 27, 2021

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