Search term returns both protease and protease inhibitors.
Found 18 search result(s) for protease.
protease inhibitors
(HIV/AIDS Research: Its History & Future Meeting)
... Protease inhibitors are antiviral drugs that inhibit viral proteases, usually used in conjunction with a transcriptase inhibitor
Dec 31, 2020
... Protease inhibitors are antiviral drugs that inhibit viral proteases, usually used in conjunction with a transcriptase inhibitor
Dec 31, 2020
RTV (ritonavir, Norvir)
(HIV/AIDS Research: Its History & Future Meeting)
... Ritonavir was originally formulated ca. 1996 as a protease inhibitor, although it is now used more frequently to inhibit enzymes that metabolizes other ...
Jan 18, 2021
... Ritonavir was originally formulated ca. 1996 as a protease inhibitor, although it is now used more frequently to inhibit enzymes that metabolizes other ...
Jan 18, 2021
Genes
(HIV/AIDS Research: Its History & Future Meeting)
... https://libwiki.cshl.edu/confluence/display/AT/gag?src=contextnavpagetreemode, short for "groupspecific antigen": encodes viral capsid proteins pro, short for "protease": encodes protease. In lentiviruses, such as HIV and HTLV, pro is part of pol. pol https://libwiki.cshl.edu/confluence/display/AT/pol?src=contextnavpagetreemode, short for "polyprotein ...
Mar 01, 2021
... https://libwiki.cshl.edu/confluence/display/AT/gag?src=contextnavpagetreemode, short for "groupspecific antigen": encodes viral capsid proteins pro, short for "protease": encodes protease. In lentiviruses, such as HIV and HTLV, pro is part of pol. pol https://libwiki.cshl.edu/confluence/display/AT/pol?src=contextnavpagetreemode, short for "polyprotein ...
Mar 01, 2021
nelfinavir (NFV)
(HIV/AIDS Research: Its History & Future Meeting)
... Protease inhibitor, patented in 1992 and approved for use in 1997
Feb 22, 2021
... Protease inhibitor, patented in 1992 and approved for use in 1997
Feb 22, 2021
lopinavir
(HIV/AIDS Research: Its History & Future Meeting)
... Protease inhibitor, patented in 1995 and approved in 2000
Feb 22, 2021
... Protease inhibitor, patented in 1995 and approved in 2000
Feb 22, 2021
Kempf, Dale J.
(HIV/AIDS Research: Its History & Future Meeting)
... Pharmaceutical chemist at Abbott Laboratories (AbbVie) and coinventor of the protease inhibitor
Feb 23, 2021
... Pharmaceutical chemist at Abbott Laboratories (AbbVie) and coinventor of the protease inhibitor
Feb 23, 2021
indinavir (IDV, Crixivan)
(HIV/AIDS Research: Its History & Future Meeting)
... Indinavir is a protease inhibitor made by Merck & Co., Inc. (Merck Sharp & Dohme), used in highly ...
Jan 11, 2021
... Indinavir is a protease inhibitor made by Merck & Co., Inc. (Merck Sharp & Dohme), used in highly ...
Jan 11, 2021
pol
(HIV/AIDS Research: Its History & Future Meeting)
... enzymes. In HIV, pol encodes the enzymes reverse transcriptase (RT), integrase (IN), HIV protease (PR), and RNase H
Aug 18, 2020
... enzymes. In HIV, pol encodes the enzymes reverse transcriptase (RT), integrase (IN), HIV protease (PR), and RNase H
Aug 18, 2020
Agouron Pharmaceuticals
(HIV/AIDS Research: Its History & Future Meeting)
... acquired by WarnerLambert in 1999, which itself was acquired by Pfizer in 2000. Agouron codeveloped the protease inhibitor nelfinavir
Feb 23, 2021
... acquired by WarnerLambert in 1999, which itself was acquired by Pfizer in 2000. Agouron codeveloped the protease inhibitor nelfinavir
Feb 23, 2021
8.2 David Ho — Unraveling of HIV Dynamics In Vivo
(HIV/AIDS Research: Its History & Future Meeting)
... Abbott. He had told me that he was working on these small molecules that will intercalate into the protease enzyme. In their enzymatic assay, inhibited protease function. Long story short, that started a collaboration that will 00:06:00 continue ...
Apr 27, 2021
... Abbott. He had told me that he was working on these small molecules that will intercalate into the protease enzyme. In their enzymatic assay, inhibited protease function. Long story short, that started a collaboration that will 00:06:00 continue ...
Apr 27, 2021
3.3 Douglas Richman: Antiviral Drug Resistance and Combination ART
(HIV/AIDS Research: Its History & Future Meeting)
... PEPFAR (President's Emergency Plan For AIDS Relief) https://libwiki.cshl.edu/confluence/pages/viewpage.action?pageId=12944797 prevention of HIV/AIDS protease https://libwiki.cshl.edu/confluence/display/AT/protease protease inhibitors https://libwiki.cshl.edu/confluence/display/AT/proteaseinhibitors Putin, Vladimir (b. 1952) https://libwiki.cshl.edu/confluence/pages/viewpage.action?pageId=15532897 reverse transcriptase https://libwiki.cshl.edu/confluence/display/AT/reversetranscriptase ... ...
Apr 27, 2021
... PEPFAR (President's Emergency Plan For AIDS Relief) https://libwiki.cshl.edu/confluence/pages/viewpage.action?pageId=12944797 prevention of HIV/AIDS protease https://libwiki.cshl.edu/confluence/display/AT/protease protease inhibitors https://libwiki.cshl.edu/confluence/display/AT/proteaseinhibitors Putin, Vladimir (b. 1952) https://libwiki.cshl.edu/confluence/pages/viewpage.action?pageId=15532897 reverse transcriptase https://libwiki.cshl.edu/confluence/display/AT/reversetranscriptase ... ...
Apr 27, 2021
2.3 Mark Harrington — The Importance of Activism to the US Response
(HIV/AIDS Research: Its History & Future Meeting)
... nuc’s, lead to drug resistance within weeks. (4) We were worried that the protease inhibitors would be approved with an inadequate evidencebase, and so we asked that they do a better ...
Apr 27, 2021
... nuc’s, lead to drug resistance within weeks. (4) We were worried that the protease inhibitors would be approved with an inadequate evidencebase, and so we asked that they do a better ...
Apr 27, 2021
3.5 Daria Hazuda: Discovery and Development of Integrase Inhibitors
(HIV/AIDS Research: Its History & Future Meeting)
... think it's worth pointing out that, in the context of HIV drug discovery, HIV protease inhibitors were really 00:05:00 among the first true examples ...
Apr 27, 2021
... think it's worth pointing out that, in the context of HIV drug discovery, HIV protease inhibitors were really 00:05:00 among the first true examples ...
Apr 27, 2021
3.1 Marty St. Clair: Discovery of AZT as the First Anti-HIV Drug
(HIV/AIDS Research: Its History & Future Meeting)
... NNRTI’s (nonnucleoside reverse transcriptase inhibitors) that are approved. 00:23:30These are PI’s (protease inhibitors), and their dates that they were approved. Everybody has seen this slide. This is a slide that the CDC ...
Apr 27, 2021
... NNRTI’s (nonnucleoside reverse transcriptase inhibitors) that are approved. 00:23:30These are PI’s (protease inhibitors), and their dates that they were approved. Everybody has seen this slide. This is a slide that the CDC ...
Apr 27, 2021
8.3 George Shaw — Transmitted/Founder HIV Genomes: What They Teach Us
(HIV/AIDS Research: Its History & Future Meeting)
... He wanted to do that, in chronic infection in order to characterize mutations across pol and protease. (12) Well, we got the idea we could apply that to acute infection ...
Apr 27, 2021
... He wanted to do that, in chronic infection in order to characterize mutations across pol and protease. (12) Well, we got the idea we could apply that to acute infection ...
Apr 27, 2021
3.6 John C. Martin — Making it Simpler: A Single Pill to Treat HIV
(HIV/AIDS Research: Its History & Future Meeting)
... want us to use ritonavir as a booster because they were worried about suboptimal protease inhibitor dosing. I don't know how big 00:16:30 ...
Apr 27, 2021
... want us to use ritonavir as a booster because they were worried about suboptimal protease inhibitor dosing. I don't know how big 00:16:30 ...
Apr 27, 2021
8.4 Robert Siliciano — The Challenge of the HIV Reservoir
(HIV/AIDS Research: Its History & Future Meeting)
... infection. You can get up to 10 logs of inhibition by some of the best protease inhibitors at peak plasma concentrations, just truly phenomenal levels of inhibition. The integrase ...
Apr 27, 2021
... infection. You can get up to 10 logs of inhibition by some of the best protease inhibitors at peak plasma concentrations, just truly phenomenal levels of inhibition. The integrase ...
Apr 27, 2021
2.4 Robert Gallo — Discoveries of Human Retrovirus, Their Linkage to Disease as Causative Agents & Preparation for the Future
(HIV/AIDS Research: Its History & Future Meeting)
... falls to Sam and BurroughsWellcome in developing AZT. In my mind, it's not 1995, '96 and the protease cocktail: 00:31:00 that's important on a practical level, but it had no new ...
Apr 27, 2021
... falls to Sam and BurroughsWellcome in developing AZT. In my mind, it's not 1995, '96 and the protease cocktail: 00:31:00 that's important on a practical level, but it had no new ...
Apr 27, 2021