Protease inhibitors are antiviral drugs that inhibit viral proteases, usually used in conjunction with a transcriptase inhibitor.
Found 15 search result(s) for protease inhibitor.
protease
(HIV/AIDS Research: Its History & Future Meeting)
... Search term returns both protease and protease inhibitors
Dec 31, 2020
... Search term returns both protease and protease inhibitors
Dec 31, 2020
3.5 Daria Hazuda: Discovery and Development of Integrase Inhibitors
(HIV/AIDS Research: Its History & Future Meeting)
... think it's worth pointing out that, in the context of HIV drug discovery, HIV protease inhibitors were really 00:05:00 among the first true examples of structurebased ... Ed Berger that you'll hear about 00:04:00 tomorrow, and the integrase ...
Apr 27, 2021
... think it's worth pointing out that, in the context of HIV drug discovery, HIV protease inhibitors were really 00:05:00 among the first true examples of structurebased ... Ed Berger that you'll hear about 00:04:00 tomorrow, and the integrase ...
Apr 27, 2021
RTV (ritonavir, Norvir)
(HIV/AIDS Research: Its History & Future Meeting)
... Ritonavir was originally formulated ca. 1996 as a protease inhibitor, although it is now used more frequently to inhibit enzymes that metabolizes other protease inhibitors
Jan 18, 2021
... Ritonavir was originally formulated ca. 1996 as a protease inhibitor, although it is now used more frequently to inhibit enzymes that metabolizes other protease inhibitors
Jan 18, 2021
nelfinavir (NFV)
(HIV/AIDS Research: Its History & Future Meeting)
... Protease inhibitor, patented in 1992 and approved for use in 1997
Feb 22, 2021
... Protease inhibitor, patented in 1992 and approved for use in 1997
Feb 22, 2021
lopinavir
(HIV/AIDS Research: Its History & Future Meeting)
... Protease inhibitor, patented in 1995 and approved in 2000
Feb 22, 2021
... Protease inhibitor, patented in 1995 and approved in 2000
Feb 22, 2021
Kempf, Dale J.
(HIV/AIDS Research: Its History & Future Meeting)
... Pharmaceutical chemist at Abbott Laboratories (AbbVie) and coinventor of the protease inhibitor
Feb 23, 2021
... Pharmaceutical chemist at Abbott Laboratories (AbbVie) and coinventor of the protease inhibitor
Feb 23, 2021
indinavir (IDV, Crixivan)
(HIV/AIDS Research: Its History & Future Meeting)
... Indinavir is a protease inhibitor made by Merck & Co., Inc. (Merck Sharp & Dohme), used in highly active ...
Jan 11, 2021
... Indinavir is a protease inhibitor made by Merck & Co., Inc. (Merck Sharp & Dohme), used in highly active ...
Jan 11, 2021
Agouron Pharmaceuticals
(HIV/AIDS Research: Its History & Future Meeting)
... acquired by WarnerLambert in 1999, which itself was acquired by Pfizer in 2000. Agouron codeveloped the protease inhibitor nelfinavir
Feb 23, 2021
... acquired by WarnerLambert in 1999, which itself was acquired by Pfizer in 2000. Agouron codeveloped the protease inhibitor nelfinavir
Feb 23, 2021
8.2 David Ho — Unraveling of HIV Dynamics In Vivo
(HIV/AIDS Research: Its History & Future Meeting)
... NYU (New York University) https://libwiki.cshl.edu/confluence/pages/viewpage.action?pageId=12944971 Pfizer https://libwiki.cshl.edu/confluence/display/AT/Pfizer pharmaceutical industry https://libwiki.cshl.edu/confluence/display/AT/pharmaceuticalindustry protease https://libwiki.cshl.edu/confluence/display/AT/protease protease inhibitors https://libwiki.cshl.edu/confluence/display/AT/proteaseinhibitors Roche https://libwiki.cshl.edu/confluence/display/AT/Roche RTV (ritonavir, Norvir) https://libwiki.cshl.edu/confluence/pages/viewpage.action?pageId=15532243 Science (journal) https://libwiki.cshl.edu/confluence/pages/viewpage.action?pageId=15532163 ... 10 years. Throughout this period, we were working on various things on pathogenesis, ...
Apr 27, 2021
... NYU (New York University) https://libwiki.cshl.edu/confluence/pages/viewpage.action?pageId=12944971 Pfizer https://libwiki.cshl.edu/confluence/display/AT/Pfizer pharmaceutical industry https://libwiki.cshl.edu/confluence/display/AT/pharmaceuticalindustry protease https://libwiki.cshl.edu/confluence/display/AT/protease protease inhibitors https://libwiki.cshl.edu/confluence/display/AT/proteaseinhibitors Roche https://libwiki.cshl.edu/confluence/display/AT/Roche RTV (ritonavir, Norvir) https://libwiki.cshl.edu/confluence/pages/viewpage.action?pageId=15532243 Science (journal) https://libwiki.cshl.edu/confluence/pages/viewpage.action?pageId=15532163 ... 10 years. Throughout this period, we were working on various things on pathogenesis, ...
Apr 27, 2021
3.3 Douglas Richman: Antiviral Drug Resistance and Combination ART
(HIV/AIDS Research: Its History & Future Meeting)
... PEPFAR (President's Emergency Plan For AIDS Relief) https://libwiki.cshl.edu/confluence/pages/viewpage.action?pageId=12944797 prevention of HIV/AIDS protease https://libwiki.cshl.edu/confluence/display/AT/protease protease inhibitors https://libwiki.cshl.edu/confluence/display/AT/proteaseinhibitors Putin, Vladimir (b. 1952) https://libwiki.cshl.edu/confluence/pages/viewpage.action?pageId=15532897 reverse transcriptase https://libwiki.cshl.edu/confluence/display/AT/reversetranscriptase Ryan ... 31 and discussed the design of combination study with Merck. This was the evaluation of indinavir (IDV, Crixivan, a ...
Apr 27, 2021
... PEPFAR (President's Emergency Plan For AIDS Relief) https://libwiki.cshl.edu/confluence/pages/viewpage.action?pageId=12944797 prevention of HIV/AIDS protease https://libwiki.cshl.edu/confluence/display/AT/protease protease inhibitors https://libwiki.cshl.edu/confluence/display/AT/proteaseinhibitors Putin, Vladimir (b. 1952) https://libwiki.cshl.edu/confluence/pages/viewpage.action?pageId=15532897 reverse transcriptase https://libwiki.cshl.edu/confluence/display/AT/reversetranscriptase Ryan ... 31 and discussed the design of combination study with Merck. This was the evaluation of indinavir (IDV, Crixivan, a ...
Apr 27, 2021
2.3 Mark Harrington — The Importance of Activism to the US Response
(HIV/AIDS Research: Its History & Future Meeting)
... nuc’s, lead to drug resistance within weeks. (4) We were worried that the protease inhibitors would be approved with an inadequate evidencebase, and so we asked that they do a better job ... ...
Apr 27, 2021
... nuc’s, lead to drug resistance within weeks. (4) We were worried that the protease inhibitors would be approved with an inadequate evidencebase, and so we asked that they do a better job ... ...
Apr 27, 2021
3.1 Marty St. Clair: Discovery of AZT as the First Anti-HIV Drug
(HIV/AIDS Research: Its History & Future Meeting)
... Everybody knows this. These are the other nucleosides that were approved. These are NNRTI’s (nonnucleoside reverse transcriptase inhibitors) that are approved. 00:23:30These are PI’s (protease inhibitors), and their dates that they were approved. Everybody has seen this slide. This is a slide that the CDC put ...
Apr 27, 2021
... Everybody knows this. These are the other nucleosides that were approved. These are NNRTI’s (nonnucleoside reverse transcriptase inhibitors) that are approved. 00:23:30These are PI’s (protease inhibitors), and their dates that they were approved. Everybody has seen this slide. This is a slide that the CDC put ...
Apr 27, 2021
3.6 John C. Martin — Making it Simpler: A Single Pill to Treat HIV
(HIV/AIDS Research: Its History & Future Meeting)
... want us to use ritonavir as a booster because they were worried about suboptimal protease inhibitor dosing. I don't know how big 00:16:30 of a concern ... ...
Apr 27, 2021
... want us to use ritonavir as a booster because they were worried about suboptimal protease inhibitor dosing. I don't know how big 00:16:30 of a concern ... ...
Apr 27, 2021
8.4 Robert Siliciano — The Challenge of the HIV Reservoir
(HIV/AIDS Research: Its History & Future Meeting)
... infection. You can get up to 10 logs of inhibition by some of the best protease inhibitors at peak plasma concentrations, just truly phenomenal levels of inhibition. The integrase inhibitors ... ...
Apr 27, 2021
... infection. You can get up to 10 logs of inhibition by some of the best protease inhibitors at peak plasma concentrations, just truly phenomenal levels of inhibition. The integrase inhibitors ... ...
Apr 27, 2021
2.4 Robert Gallo — Discoveries of Human Retrovirus, Their Linkage to Disease as Causative Agents & Preparation for the Future
(HIV/AIDS Research: Its History & Future Meeting)
... falls to Sam and BurroughsWellcome in developing AZT. In my mind, it's not 1995, '96 and the protease cocktail: 00:31:00 that's important on a practical level, but it had no new ...
Apr 27, 2021
... falls to Sam and BurroughsWellcome in developing AZT. In my mind, it's not 1995, '96 and the protease cocktail: 00:31:00 that's important on a practical level, but it had no new ...
Apr 27, 2021