Pioneered by Gertrude B. Elion (1918–1999), rational drug discovery is the process of finding new medications by targeting a specific biomolecule that is key to the disease process.
Found 7 search result(s) for rational design.
Elion, Gertrude B. "Trudy" (1918–1999)
(HIV/AIDS Research: Its History & Future Meeting)
... pharmacologist. Received the 1988 Nobel Prize in Medicine or Physiology for the developing the principles behind rational drug design
Jan 06, 2021
... pharmacologist. Received the 1988 Nobel Prize in Medicine or Physiology for the developing the principles behind rational drug design
Jan 06, 2021
6.4 Barton Haynes — Development of HIV Vaccine: Steps and Missteps
(HIV/AIDS Research: Its History & Future Meeting)
... Takayuki Ota, Oleksandr Kalyuzhniy, Andrew McGuire, Devin Sok, et al. “Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors.” Science 340, no. 6133 (May ... ...
Apr 27, 2021
... Takayuki Ota, Oleksandr Kalyuzhniy, Andrew McGuire, Devin Sok, et al. “Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors.” Science 340, no. 6133 (May ... ...
Apr 27, 2021
6.2 Dennis Burton — How Does HIV Evade the Antibody Response?
(HIV/AIDS Research: Its History & Future Meeting)
... think that, and this again is revolutionary thinking actually in a way from the field in terms of vaccine design. Vaccine design to date is, you get the same vaccine three times, usually or maybe twice ... ...
Apr 27, 2021
... think that, and this again is revolutionary thinking actually in a way from the field in terms of vaccine design. Vaccine design to date is, you get the same vaccine three times, usually or maybe twice ... ...
Apr 27, 2021
3.5 Daria Hazuda: Discovery and Development of Integrase Inhibitors
(HIV/AIDS Research: Its History & Future Meeting)
... pocket at the enzyme active site. And it was on the basis of this structural motif, that the structural model that the chemists then rationally design alternatives to the diketo acid motif, the naphthyridine carboxamides. 00:17:30 This allowed ... ...
Apr 27, 2021
... pocket at the enzyme active site. And it was on the basis of this structural motif, that the structural model that the chemists then rationally design alternatives to the diketo acid motif, the naphthyridine carboxamides. 00:17:30 This allowed ... ...
Apr 27, 2021
Session 10: What Have We Learned?
(HIV/AIDS Research: Its History & Future Meeting)
... Relief) https://libwiki.cshl.edu/confluence/pages/viewpage.action?pageId=12944797 polio, polio vaccine https://libwiki.cshl.edu/confluence/display/AT/polio%2Cpoliovaccine preexposure prophylaxis (PrEP) https://libwiki.cshl.edu/confluence/pages/viewpage.action?pageId=12944719 rational drug design https://libwiki.cshl.edu/confluence/display/AT/rationaldrugdesign San Francisco https://libwiki.cshl.edu/confluence/display/AT/SanFrancisco Science (journal) https://libwiki.cshl.edu/confluence/pages/viewpage.action?pageId=15532163 Session 9: Public ... ...
Apr 27, 2021
... Relief) https://libwiki.cshl.edu/confluence/pages/viewpage.action?pageId=12944797 polio, polio vaccine https://libwiki.cshl.edu/confluence/display/AT/polio%2Cpoliovaccine preexposure prophylaxis (PrEP) https://libwiki.cshl.edu/confluence/pages/viewpage.action?pageId=12944719 rational drug design https://libwiki.cshl.edu/confluence/display/AT/rationaldrugdesign San Francisco https://libwiki.cshl.edu/confluence/display/AT/SanFrancisco Science (journal) https://libwiki.cshl.edu/confluence/pages/viewpage.action?pageId=15532163 Session 9: Public ... ...
Apr 27, 2021
8.6 David Baltimore — Bringing it to an End (And Where Are We Going?)
(HIV/AIDS Research: Its History & Future Meeting)
... got behind it. It wasn't the number that we calculated on 00:05:00 any rational basis. It was impressive to see that a couple of years later we were spending a billion ...
Apr 27, 2021
... got behind it. It wasn't the number that we calculated on 00:05:00 any rational basis. It was impressive to see that a couple of years later we were spending a billion ...
Apr 27, 2021
Session 7: Prospects for an HIV Vaccine
(HIV/AIDS Research: Its History & Future Meeting)
... I have is, what was actually the mechanism that led to not consider the possibility of doing a better design trial in which you actually used in parallel also the alum hydrogel. Because ...
Apr 27, 2021
... I have is, what was actually the mechanism that led to not consider the possibility of doing a better design trial in which you actually used in parallel also the alum hydrogel. Because ...
Apr 27, 2021