Gene (DNA, RNA) sequencing
Found 39 search result(s) for sequence OR sequencing.
Kozak consensus sequence
(HIV/AIDS Research: Its History & Future Meeting)
... Kozak sequence, named after molecular biologist Marilyn Kozak (b. 1943), is the highly conserved ...
Feb 25, 2021
... Kozak sequence, named after molecular biologist Marilyn Kozak (b. 1943), is the highly conserved ...
Feb 25, 2021
4.4 Michael Worobey — Spread of HIV in the New World
(HIV/AIDS Research: Its History & Future Meeting)
... our archival sequences have made is to now be able to do comparative genetics on sequences in the past. You take this '59 sequence and this 1960 sequence and you can now step back in time, forget about inferences from ...
Apr 27, 2021
... our archival sequences have made is to now be able to do comparative genetics on sequences in the past. You take this '59 sequence and this 1960 sequence and you can now step back in time, forget about inferences from ...
Apr 27, 2021
8.3 George Shaw — Transmitted/Founder HIV Genomes: What They Teach Us
(HIV/AIDS Research: Its History & Future Meeting)
... genetic makeup of these viruses, we can infer the exact 10 kilobase nucleotides sequence, and that's 00:06:30 the inferred proteome of that virus. We can do ...
Apr 27, 2021
... genetic makeup of these viruses, we can infer the exact 10 kilobase nucleotides sequence, and that's 00:06:30 the inferred proteome of that virus. We can do ...
Apr 27, 2021
8.1 John Mellors — MACS and Beyond: Epidemiology, Viremia and Pathogenesis
(HIV/AIDS Research: Its History & Future Meeting)
... back to the patient, got CD4 cells isolated 00:17:30 virus, sequenced it, and the sequences of the isolated infectious virus matched the plasma viremia and the proviral DNA. (28) This was the first ... ...
Apr 27, 2021
... back to the patient, got CD4 cells isolated 00:17:30 virus, sequenced it, and the sequences of the isolated infectious virus matched the plasma viremia and the proviral DNA. (28) This was the first ... ...
Apr 27, 2021
5.3 Michael Malim — Discovery of APOBEC Restriction
(HIV/AIDS Research: Its History & Future Meeting)
... cytidine ring in polynucleotides, RNA or DNA, converting it to uridine, and therefore changing the coding sequence. 00:10:00 So the obvious question was, was APOBEC3G affecting the sequence of HIV? Now, at this time, we teamed up with a group in Cambridge led by Michael ...
Apr 27, 2021
... cytidine ring in polynucleotides, RNA or DNA, converting it to uridine, and therefore changing the coding sequence. 00:10:00 So the obvious question was, was APOBEC3G affecting the sequence of HIV? Now, at this time, we teamed up with a group in Cambridge led by Michael ...
Apr 27, 2021
8.4 Robert Siliciano — The Challenge of the HIV Reservoir
(HIV/AIDS Research: Its History & Future Meeting)
... rT should have a point mutation, and there should be, in other words, a large number of sequences that are close to the dominant sequence. In fact, that's not what you see. 00:23:00 The dominant sequence ... ...
Apr 27, 2021
... rT should have a point mutation, and there should be, in other words, a large number of sequences that are close to the dominant sequence. In fact, that's not what you see. 00:23:00 The dominant sequence ... ...
Apr 27, 2021
5.6 Michael Emerman — Host-virus Co-evolution
(HIV/AIDS Research: Its History & Future Meeting)
... bound to Vif, and it's someplace in this region. The way we do this is not just by looking at sequences, but actually doing functional studies. There is an alanine at this sequence. This is in the guenons (cercopithecus monkeys) down here. The viruses which affects those guenons ...
Apr 27, 2021
... bound to Vif, and it's someplace in this region. The way we do this is not just by looking at sequences, but actually doing functional studies. There is an alanine at this sequence. This is in the guenons (cercopithecus monkeys) down here. The viruses which affects those guenons ...
Apr 27, 2021
4.1 Ronald Desrosiers — The Origin of SIVmac: Non-human Primate Models for HIV
(HIV/AIDS Research: Its History & Future Meeting)
... provided sera to her. Is that right Beatrice? Yes. Beatrice used her outstanding sequencing capabilities, and indeed showed that the sequences present in these two baboons were of the SIVagm of the vervet subtype, so indeed they were ... ...
Apr 27, 2021
... provided sera to her. Is that right Beatrice? Yes. Beatrice used her outstanding sequencing capabilities, and indeed showed that the sequences present in these two baboons were of the SIVagm of the vervet subtype, so indeed they were ... ...
Apr 27, 2021
1.5 John Coffin — The Origin of Molecular Retrovirology
(HIV/AIDS Research: Its History & Future Meeting)
... 00 an important sync transcriptional control signals for the virus. As they say, there wasn't much sequencing done. In fact, I did publish a paper, a sequencing paper about this time, the nucleotide sequence at the site of the DNA synthesis, “The 102nd nucleotide is U” (21)—actually ...
Apr 27, 2021
... 00 an important sync transcriptional control signals for the virus. As they say, there wasn't much sequencing done. In fact, I did publish a paper, a sequencing paper about this time, the nucleotide sequence at the site of the DNA synthesis, “The 102nd nucleotide is U” (21)—actually ...
Apr 27, 2021
4.3 Beatrice Hahn — Apes to Humans: The Origin of HIV
(HIV/AIDS Research: Its History & Future Meeting)
... she did the estimation, 00:39:30 she did it without those sequences. Then she put those sequences in as a query and said, "My algorithm, when would you tell me that these sequences ... ...
Nov 11, 2021
... she did the estimation, 00:39:30 she did it without those sequences. Then she put those sequences in as a query and said, "My algorithm, when would you tell me that these sequences ... ...
Nov 11, 2021
2.5 Françoise Barré-Sinoussi — Discovery of HIV
(HIV/AIDS Research: Its History & Future Meeting)
... patients. Characterization of the genome of the virus, that was done between 1984, 1985. (17) Cloning and sequencing of the genome, the first complete 00:23:00 sequence was obtained and published in 1984 1985, showing that it was a unique and very complex genome distinct ...
Apr 27, 2021
... patients. Characterization of the genome of the virus, that was done between 1984, 1985. (17) Cloning and sequencing of the genome, the first complete 00:23:00 sequence was obtained and published in 1984 1985, showing that it was a unique and very complex genome distinct ...
Apr 27, 2021
1.4 Robin Weiss — Retrovirus History and Early Searches for Human Retroviruses
(HIV/AIDS Research: Its History & Future Meeting)
... went on to 00:21:00 sequence the lentivirus Visna. (28) That came after sequencing HIV and their genome structure and open reading frames looked almost identical, and then Matt ... owned up to one we thought was human that turned out to be an endogenous rabbit ...
Apr 27, 2021
... went on to 00:21:00 sequence the lentivirus Visna. (28) That came after sequencing HIV and their genome structure and open reading frames looked almost identical, and then Matt ... owned up to one we thought was human that turned out to be an endogenous rabbit ...
Apr 27, 2021
4.2 Martine Peeters — On the Road to HIV: Primate Lentiviruses
(HIV/AIDS Research: Its History & Future Meeting)
... been isolated in Gabon, the electron microscopy has also been done in Gabon and the sequence analyzed has been done at the Pasteur Institute and confirmed that the virus was most closely ...
Apr 27, 2021
... been isolated in Gabon, the electron microscopy has also been done in Gabon and the sequence analyzed has been done at the Pasteur Institute and confirmed that the virus was most closely ...
Apr 27, 2021
3.3 Douglas Richman: Antiviral Drug Resistance and Combination ART
(HIV/AIDS Research: Its History & Future Meeting)
... reduction in drug susceptibility over a period of months. Subsequently, we cloned and population sequenced and then Brendan Larder and Sharon D. Kemp, his 00:03:00 wife ...
Apr 27, 2021
... reduction in drug susceptibility over a period of months. Subsequently, we cloned and population sequenced and then Brendan Larder and Sharon D. Kemp, his 00:03:00 wife ...
Apr 27, 2021
1.6 Harold Varmus — Animal Retroviruses and Cancer Research
(HIV/AIDS Research: Its History & Future Meeting)
... now know from essentially all metazoa, you can find homologous sequences that will hybridize or at least show by DNA sequencing, as we've subsequently demonstrated, that the src gene is present in normal cells in a slightly different ...
Apr 27, 2021
... now know from essentially all metazoa, you can find homologous sequences that will hybridize or at least show by DNA sequencing, as we've subsequently demonstrated, that the src gene is present in normal cells in a slightly different ...
Apr 27, 2021
5.4 Edward Berger — Discovery of HIV Co-receptors
(HIV/AIDS Research: Its History & Future Meeting)
... We ended up isolating a single 00:12:30 cDNA clone, and the sequence encoded what looked like a G proteincoupled receptor. It was actually a molecule that was already ...
Apr 27, 2021
... We ended up isolating a single 00:12:30 cDNA clone, and the sequence encoded what looked like a G proteincoupled receptor. It was actually a molecule that was already ...
Apr 27, 2021
1.7 Max Essex — From Feline Leukemia Virus to AIDS in Africa
(HIV/AIDS Research: Its History & Future Meeting)
... match the sequence of the amino acids read out from the amino terminus end to the sequence for the virus, which by that time, was being generated by Flossie WongStaal and Bill Haseltine (b ... remarkably creative at the time—we certainly didn't invent it—It was radiolabeled amino acid ...
Apr 27, 2021
... match the sequence of the amino acids read out from the amino terminus end to the sequence for the virus, which by that time, was being generated by Flossie WongStaal and Bill Haseltine (b ... remarkably creative at the time—we certainly didn't invent it—It was radiolabeled amino acid ...
Apr 27, 2021
5.1 Flossie Wong-Staal — Discovery of Human Retroviral Transactivators
(HIV/AIDS Research: Its History & Future Meeting)
... active clone because now you can introduce any mutation in the coding sequence, or even noncoding sequence, and determine its relevance, not only in infection 00:10:00 but in its cytopathicity ... ...
Apr 27, 2021
... active clone because now you can introduce any mutation in the coding sequence, or even noncoding sequence, and determine its relevance, not only in infection 00:10:00 but in its cytopathicity ... ...
Apr 27, 2021
nuclear export signal
(HIV/AIDS Research: Its History & Future Meeting)
... amino acid sequence that targets a protein for export out of the nucleus and into the cytoplasm
Jan 26, 2021
... amino acid sequence that targets a protein for export out of the nucleus and into the cytoplasm
Jan 26, 2021
transposon
(HIV/AIDS Research: Its History & Future Meeting)
... transposon, also transposable element or "jumping gene," a DNA sequence that can change its position within a genome
Aug 26, 2020
... transposon, also transposable element or "jumping gene," a DNA sequence that can change its position within a genome
Aug 26, 2020
endogenous retrovirus (ERV)
(HIV/AIDS Research: Its History & Future Meeting)
... endogenous retrovirus (ERV): a DNA sequence derived from a retrovirus (provirus) more or less permanently embedded in the host organism's ...
Aug 19, 2020
... endogenous retrovirus (ERV): a DNA sequence derived from a retrovirus (provirus) more or less permanently embedded in the host organism's ...
Aug 19, 2020
Yoshida, Mitsuaki (吉田 光昭, b. 1939)
(HIV/AIDS Research: Its History & Future Meeting)
... Mitsuaki Yoshida (吉田 光昭, b. 1939), Japanese virologist. Sequenced the HTLVI genome in 1983
Jan 26, 2021
... Mitsuaki Yoshida (吉田 光昭, b. 1939), Japanese virologist. Sequenced the HTLVI genome in 1983
Jan 26, 2021
molecular clock
(HIV/AIDS Research: Its History & Future Meeting)
... called an evolutionary clock, this uses the predictable and calibrated mutation rate of DNA and other sequenceable biomolecules to date the divergence of two different evolutionary lineages
Jan 24, 2021
... called an evolutionary clock, this uses the predictable and calibrated mutation rate of DNA and other sequenceable biomolecules to date the divergence of two different evolutionary lineages
Jan 24, 2021
microsatellite, microsatellite analysis, short tandem repeats (STRs)
(HIV/AIDS Research: Its History & Future Meeting)
... microsatellite is a short (2–6 base pairs), repetitive DNA sequence or motif, found in noncoding regions of the genome. Microsatellites are unstable across generations and are thus ...
Jan 24, 2021
... microsatellite is a short (2–6 base pairs), repetitive DNA sequence or motif, found in noncoding regions of the genome. Microsatellites are unstable across generations and are thus ...
Jan 24, 2021
Genes
(HIV/AIDS Research: Its History & Future Meeting)
... target cells and gain entry. LTR (long terminal repeat) https://libwiki.cshl.edu/confluence/pages/viewpage.action?pageId=12943732&src=contextnavpagetreemode: identical sequences of DNA of several hundred base pairs located at each end of the viral genome
Mar 01, 2021
... target cells and gain entry. LTR (long terminal repeat) https://libwiki.cshl.edu/confluence/pages/viewpage.action?pageId=12943732&src=contextnavpagetreemode: identical sequences of DNA of several hundred base pairs located at each end of the viral genome
Mar 01, 2021
LTR (long terminal repeat)
(HIV/AIDS Research: Its History & Future Meeting)
... LTRs (long terminal repeats) are identical sequences of DNA of several hundred base pairs located at each end (the 5' end ...
Aug 18, 2020
... LTRs (long terminal repeats) are identical sequences of DNA of several hundred base pairs located at each end (the 5' end ...
Aug 18, 2020
1.1 James D. Watson — Welcome
(HIV/AIDS Research: Its History & Future Meeting)
... 00 This should be a truly exciting meeting. We had one on the history of DNA sequencing and all the technology developed two years ago. (1) It is extraordinary just how ...
Apr 27, 2021
... 00 This should be a truly exciting meeting. We had one on the history of DNA sequencing and all the technology developed two years ago. (1) It is extraordinary just how ...
Apr 27, 2021
5.5 Andrew Rice — Mechanism of tat Transactivation
(HIV/AIDS Research: Its History & Future Meeting)
... Desrosiers: Maybe you said this and I missed it, but if one were to change the TAR sequence to something more innocuous 00:23:00 or not folded, would you predict ...
Apr 27, 2021
... Desrosiers: Maybe you said this and I missed it, but if one were to change the TAR sequence to something more innocuous 00:23:00 or not folded, would you predict ...
Apr 27, 2021
2.0 Michael Gottlieb — Introduction to Session 2
(HIV/AIDS Research: Its History & Future Meeting)
... cases 00:01:00 were dramatic and we saw them in rapid sequence and we were able to put it together. This was published in MMWR. We collaborated with CDC's ...
May 25, 2021
... cases 00:01:00 were dramatic and we saw them in rapid sequence and we were able to put it together. This was published in MMWR. We collaborated with CDC's ...
May 25, 2021
3.2 Samuel Broder: The First Clinical Trials of Antiretroviral Drugs
(HIV/AIDS Research: Its History & Future Meeting)
... didn't have PCR—realtime PCR. We didn't have whole genome sequencing and assembly, we didn't have the internet, we didn't have Facebook. Maybe ...
Apr 27, 2021
... didn't have PCR—realtime PCR. We didn't have whole genome sequencing and assembly, we didn't have the internet, we didn't have Facebook. Maybe ...
Apr 27, 2021
6.5 Emilio Emini — Issues in HIV Vaccine Development: Will the Future be any Easier than the Past?
(HIV/AIDS Research: Its History & Future Meeting)
... determinant. This was a figure from the paper where we looked at a number of different peptide sequences and had the very early naive concept back in those days of, why can't ...
Apr 27, 2021
... determinant. This was a figure from the paper where we looked at a number of different peptide sequences and had the very early naive concept back in those days of, why can't ...
Apr 27, 2021
2.4 Robert Gallo — Discoveries of Human Retrovirus, Their Linkage to Disease as Causative Agents & Preparation for the Future
(HIV/AIDS Research: Its History & Future Meeting)
... last night, HTLVII—you know, it's amazingly similar in its genome and sequence homology to HTLVI, yet it's very poorly pathogenic, not true of HTLVI, as I'll ...
Apr 27, 2021
... last night, HTLVII—you know, it's amazingly similar in its genome and sequence homology to HTLVI, yet it's very poorly pathogenic, not true of HTLVI, as I'll ...
Apr 27, 2021
6.1 Sharon Hillier — Development and Application of Pre-exposure Prophylaxis (PrEP)
(HIV/AIDS Research: Its History & Future Meeting)
... drug resistance although John Mellors' lab is still looking at some of the deep sequencing on all the seroconverters from the study. What we saw overall was disappointing, at least ...
Apr 27, 2021
... drug resistance although John Mellors' lab is still looking at some of the deep sequencing on all the seroconverters from the study. What we saw overall was disappointing, at least ...
Apr 27, 2021
6.4 Barton Haynes — Development of HIV Vaccine: Steps and Missteps
(HIV/AIDS Research: Its History & Future Meeting)
... studies, these are the observations that have been made. This is a visual representation 00:15:30 of the sequence of the envelope undergoing evolution. (9) The single transmitted founder virus responding to the autologous ...
Apr 27, 2021
... studies, these are the observations that have been made. This is a visual representation 00:15:30 of the sequence of the envelope undergoing evolution. (9) The single transmitted founder virus responding to the autologous ...
Apr 27, 2021
6.2 Dennis Burton — How Does HIV Evade the Antibody Response?
(HIV/AIDS Research: Its History & Future Meeting)
... different viruses that were really quite dispersed in terms of 00:04:30 sequence. That was really the point at which, for me, anyway, we started to think about vaccines ...
Apr 27, 2021
... different viruses that were really quite dispersed in terms of 00:04:30 sequence. That was really the point at which, for me, anyway, we started to think about vaccines ...
Apr 27, 2021
8.5 Sharon Lewin — Research to a Cure: A Possible Goal?
(HIV/AIDS Research: Its History & Future Meeting)
... surface? Actually, an answer to Paul's question, Sarah Palmer recently did some sequencing on some samples that we had in a clinical trial looking at defective virus, DNA ...
Apr 27, 2021
... surface? Actually, an answer to Paul's question, Sarah Palmer recently did some sequencing on some samples that we had in a clinical trial looking at defective virus, DNA ...
Apr 27, 2021
3.5 Daria Hazuda: Discovery and Development of Integrase Inhibitors
(HIV/AIDS Research: Its History & Future Meeting)
... were three steps. We knew that the enzyme had to bind to very specific sequences at the ends of the viral DNA (LTRs) . The context of that complex, the preintegration complex 00:07 ...
Apr 27, 2021
... were three steps. We knew that the enzyme had to bind to very specific sequences at the ends of the viral DNA (LTRs) . The context of that complex, the preintegration complex 00:07 ...
Apr 27, 2021
6.7 Salim Abdool Karim — Stopping the Spread of HIV in Developing Countries
(HIV/AIDS Research: Its History & Future Meeting)
... over 10,000 people in this rural and urban community in the KwaZuluNatal Midlands and where we sequenced well over a oneandahalf thousand viruses and we tried to look at all of the clusters ...
Apr 27, 2021
... over 10,000 people in this rural and urban community in the KwaZuluNatal Midlands and where we sequenced well over a oneandahalf thousand viruses and we tried to look at all of the clusters ...
Apr 27, 2021
8.6 David Baltimore — Bringing it to an End (And Where Are We Going?)
(HIV/AIDS Research: Its History & Future Meeting)
... can squeeze tight, and you can put an antibody gene into the vector, use it to a sequence between the heavy chain and light chain, provide other goodies and get a good ...
Apr 27, 2021
... can squeeze tight, and you can put an antibody gene into the vector, use it to a sequence between the heavy chain and light chain, provide other goodies and get a good ...
Apr 27, 2021