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Structure-based drug design uses knowledge of the three-dimensional structure of the target molecule or enzyme complex. Drugs designed this way can either target the target molecule's active site, or target any other sites or surfaces of the molecule if possible.

Found 2 search result(s) for "structure-based drug design".

Page: 3.5 Daria Hazuda: Discovery and Development of Integrase Inhibitors (HIV/AIDS Research: Its History & Future Meeting)
... structurebased drug design, and all the next generation agents certainly relied on structurebased drug design. In the case of integrase, we didn't have a relevant structure information. We had structural information on each of the independent domains when we ...
Apr 27, 2021
Page: 5.4 Edward Berger — Discovery of HIV Co-receptors (HIV/AIDS Research: Its History & Future Meeting)
... lot of that RNA. 00:30:12 END OF VIDEO   #structural biology #structurebased drug design Citations Dalgleish, Angus G., Peter C. L. Beverley, Paul R ... ...
Apr 27, 2021

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