Non-nucleoside reverse-transcriptase inhibitors (NNRTIs) are, as the name suggests, drugs that inhibit the function of viral reverse transcriptase, but not as nucleoside analogues. Instead, NNRTIs target features of reverse transcriptase other than domains responsible for DNA polymerization.
Found 8 search result(s) for NNRTI.
nevirapine (NVP, Viramune)
(HIV/AIDS Research: Its History & Future Meeting)
... nonnucleoside reversetranscriptase inhibitor (NNRTI), first approved for use in 1996
Jan 08, 2021
... nonnucleoside reversetranscriptase inhibitor (NNRTI), first approved for use in 1996
Jan 08, 2021
EFV (efavirenz)
(HIV/AIDS Research: Its History & Future Meeting)
... EFV (efavirenz, Sustiva) is an NNRTI, and was approved by the FDA for use in 1998. It is sold as a triple combination with FTC (emtricitabine) and tenofovir ...
Jan 11, 2021
... EFV (efavirenz, Sustiva) is an NNRTI, and was approved by the FDA for use in 1998. It is sold as a triple combination with FTC (emtricitabine) and tenofovir ...
Jan 11, 2021
3.3 Douglas Richman: Antiviral Drug Resistance and Combination ART
(HIV/AIDS Research: Its History & Future Meeting)
... looked at was the appearance of mutations in the target enzyme with this nonnucleoside RT (reverse transcriptase) inhibitor (NNRTI). What we showed is that—we 00:07:00 used two different ...
Apr 27, 2021
... looked at was the appearance of mutations in the target enzyme with this nonnucleoside RT (reverse transcriptase) inhibitor (NNRTI). What we showed is that—we 00:07:00 used two different ...
Apr 27, 2021
6.1 Sharon Hillier — Development and Application of Pre-exposure Prophylaxis (PrEP)
(HIV/AIDS Research: Its History & Future Meeting)
... slowly releases the ARV (antiretroviral) drug dapivirine as a nonnucleoside reverse transcriptase inhibitor (NNRTI). The entire dose over an entire month of use is 4mg, contrast that to 9gm of oral ...
Apr 27, 2021
... slowly releases the ARV (antiretroviral) drug dapivirine as a nonnucleoside reverse transcriptase inhibitor (NNRTI). The entire dose over an entire month of use is 4mg, contrast that to 9gm of oral ...
Apr 27, 2021
8.1 John Mellors — MACS and Beyond: Epidemiology, Viremia and Pathogenesis
(HIV/AIDS Research: Its History & Future Meeting)
... preexistence of nelfinavir resistance mutants, or to the poor adherence to nelfinavir. We also looked at NNRTI (nonnucleoside reversetranscriptase inhibitor) based regimens, and there was no difference. We concluded from this that current ...
Apr 27, 2021
... preexistence of nelfinavir resistance mutants, or to the poor adherence to nelfinavir. We also looked at NNRTI (nonnucleoside reversetranscriptase inhibitor) based regimens, and there was no difference. We concluded from this that current ...
Apr 27, 2021
1.5 John Coffin — The Origin of Molecular Retrovirology
(HIV/AIDS Research: Its History & Future Meeting)
... transcriptase assay #nucleoside reverse transcriptase inhibitors (NRTIs) #nonnucleoside reversetranscriptase inhibitors (NNRTIs) However, in the early days, there was a lot of work done, in completely misguided experiment on the idea ...
Apr 27, 2021
... transcriptase assay #nucleoside reverse transcriptase inhibitors (NRTIs) #nonnucleoside reversetranscriptase inhibitors (NNRTIs) However, in the early days, there was a lot of work done, in completely misguided experiment on the idea ...
Apr 27, 2021
3.1 Marty St. Clair: Discovery of AZT as the First Anti-HIV Drug
(HIV/AIDS Research: Its History & Future Meeting)
... HAART, highly active antiretroviral therapy—primarily two nuc’s (nucleoside analogues) and an NNRTI or two nuc’s and a PI—what changed is the death rate. We didn't change ...
Apr 27, 2021
... HAART, highly active antiretroviral therapy—primarily two nuc’s (nucleoside analogues) and an NNRTI or two nuc’s and a PI—what changed is the death rate. We didn't change ...
Apr 27, 2021
6.5 Emilio Emini — Issues in HIV Vaccine Development: Will the Future be any Easier than the Past?
(HIV/AIDS Research: Its History & Future Meeting)
... New York Hospital–Cornell Medical Center https://libwiki.cshl.edu/confluence/pages/viewpage.action?pageId=15532602 nonnucleoside reversetranscriptase inhibitors (NNRTIs) https://libwiki.cshl.edu/confluence/pages/viewpage.action?pageId=12944448 papillomavirus https://libwiki.cshl.edu/confluence/display/AT/papillomavirus Pfizer https://libwiki.cshl.edu/confluence/display/AT/Pfizer pharmaceutical industry https://libwiki.cshl.edu/confluence/display/AT/pharmaceuticalindustry Picker, Louis ...
Apr 27, 2021
... New York Hospital–Cornell Medical Center https://libwiki.cshl.edu/confluence/pages/viewpage.action?pageId=15532602 nonnucleoside reversetranscriptase inhibitors (NNRTIs) https://libwiki.cshl.edu/confluence/pages/viewpage.action?pageId=12944448 papillomavirus https://libwiki.cshl.edu/confluence/display/AT/papillomavirus Pfizer https://libwiki.cshl.edu/confluence/display/AT/Pfizer pharmaceutical industry https://libwiki.cshl.edu/confluence/display/AT/pharmaceuticalindustry Picker, Louis ...
Apr 27, 2021