Kaposi's sarcoma-associated herpesvirus (KSHV), or more formally Human gammaherpesvirus 8 or (HHV-8) causes Kaposi's sarcoma (KS). Identified in 1994.
Found 40 search result(s) for HHV-8.
2.1 Paul Volberding — The First Patients
(HIV/AIDS Research: Its History & Future Meeting)
Paul Volberding: 00:00:00 Great. Well, it's a thrill to be here, look around the room, and lots of very important people that did so much with this epidemic. Thanks especially to Bob Gallo for inviting me. Heard about this I ...
Apr 27, 2021
Paul Volberding: 00:00:00 Great. Well, it's a thrill to be here, look around the room, and lots of very important people that did so much with this epidemic. Thanks especially to Bob Gallo for inviting me. Heard about this I ...
Apr 27, 2021
Session 8: Pathogenesis and Prospects
(HIV/AIDS Research: Its History & Future Meeting)
Chairs: Alan Perelson (Los Alamos National Laboratory, Santa Fe Institute) and Ashley Haase (University of Minnesota) 8.1 John Mellors — MACS and Beyond: Epidemiology, Viremia and Pathogenesis https://libwiki.cshl.edu/confluence/pages/viewpage.action?pageId=12943574&src=contextnavpagetreemode 8.2 David Ho — Unraveling of HIV Dynamics In Vivo ...
Apr 27, 2021
Chairs: Alan Perelson (Los Alamos National Laboratory, Santa Fe Institute) and Ashley Haase (University of Minnesota) 8.1 John Mellors — MACS and Beyond: Epidemiology, Viremia and Pathogenesis https://libwiki.cshl.edu/confluence/pages/viewpage.action?pageId=12943574&src=contextnavpagetreemode 8.2 David Ho — Unraveling of HIV Dynamics In Vivo ...
Apr 27, 2021
models (model systems, model organisms, modeling)
(HIV/AIDS Research: Its History & Future Meeting)
... Models of Biochemical Mechanisms, 1840 1960. History, Philosophy and Theory of the Life Sciences 8. Dordrecht: Springer, 2015
Aug 23, 2020
... Models of Biochemical Mechanisms, 1840 1960. History, Philosophy and Theory of the Life Sciences 8. Dordrecht: Springer, 2015
Aug 23, 2020
8.2 David Ho — Unraveling of HIV Dynamics In Vivo
(HIV/AIDS Research: Its History & Future Meeting)
... all the subjects who could stay on the medicines, this is exactly what we saw. (8) The viral load becoming undetectable and staying so for approximately one year. I ...
Apr 27, 2021
... all the subjects who could stay on the medicines, this is exactly what we saw. (8) The viral load becoming undetectable and staying so for approximately one year. I ...
Apr 27, 2021
1.4 Robin Weiss — Retrovirus History and Early Searches for Human Retroviruses
(HIV/AIDS Research: Its History & Future Meeting)
... marked in red, the HTLVs and the HIVs, and I've also put up a couple in realm of the 8% of the human genome that represents fossil retroviral infections. 00:04:30 A tremendous ...
Apr 27, 2021
... marked in red, the HTLVs and the HIVs, and I've also put up a couple in realm of the 8% of the human genome that represents fossil retroviral infections. 00:04:30 A tremendous ...
Apr 27, 2021
8.1 John Mellors — MACS and Beyond: Epidemiology, Viremia and Pathogenesis
(HIV/AIDS Research: Its History & Future Meeting)
... weekends. That resulted 00:04:00 in collaboration with Chiron, John Todd, and others. (8) The data from the Pittsburgh MACS showing this remarkable stratification of time to death by, in this instance ...
Apr 27, 2021
... weekends. That resulted 00:04:00 in collaboration with Chiron, John Todd, and others. (8) The data from the Pittsburgh MACS showing this remarkable stratification of time to death by, in this instance ...
Apr 27, 2021
5.4 Edward Berger — Discovery of HIV Co-receptors
(HIV/AIDS Research: Its History & Future Meeting)
... molecule and the chemokine 00:13:30 receptor people have a nomenclature system. (8, 9) So, very quickly, the name "fusin" was replaced with the name CXCR4. "Fusin ...
Apr 27, 2021
... molecule and the chemokine 00:13:30 receptor people have a nomenclature system. (8, 9) So, very quickly, the name "fusin" was replaced with the name CXCR4. "Fusin ...
Apr 27, 2021
8.5 Sharon Lewin — Research to a Cure: A Possible Goal?
(HIV/AIDS Research: Its History & Future Meeting)
... mine, other than cure, about what determines variability in immune reconstitution. (8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18 ...
Apr 27, 2021
... mine, other than cure, about what determines variability in immune reconstitution. (8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18 ...
Apr 27, 2021
3.3 Douglas Richman: Antiviral Drug Resistance and Combination ART
(HIV/AIDS Research: Its History & Future Meeting)
... mid'70s that the definition of an antiviral drug is one that can select for drug resistance. (8) 00:17:30 That is a pretty reliable one that rules out nonspecific effects ...
Apr 27, 2021
... mid'70s that the definition of an antiviral drug is one that can select for drug resistance. (8) 00:17:30 That is a pretty reliable one that rules out nonspecific effects ...
Apr 27, 2021
6.4 Barton Haynes — Development of HIV Vaccine: Steps and Missteps
(HIV/AIDS Research: Its History & Future Meeting)
... talking earlier about the evanescent nature of the antibody response due to envelope vaccines. (8) The efficacy was 60% through 12 months and 31.2% at nearly two years. We ...
Apr 27, 2021
... talking earlier about the evanescent nature of the antibody response due to envelope vaccines. (8) The efficacy was 60% through 12 months and 31.2% at nearly two years. We ...
Apr 27, 2021
8.4 Robert Siliciano — The Challenge of the HIV Reservoir
(HIV/AIDS Research: Its History & Future Meeting)
... persistence of HIV in patients on a suppressive 00:07:00 antiretroviral therapy. (6, 8, 9) This was the beginning of the Dark Ages for HIV cure research because, as you can ...
Apr 27, 2021
... persistence of HIV in patients on a suppressive 00:07:00 antiretroviral therapy. (6, 8, 9) This was the beginning of the Dark Ages for HIV cure research because, as you can ...
Apr 27, 2021
4.2 Martine Peeters — On the Road to HIV: Primate Lentiviruses
(HIV/AIDS Research: Its History & Future Meeting)
... noninvasive way, and she showed the feasibility to detect SIV infection in feces and urine. (8, 9, 10) She did it initially on experimentally infected chimpanzees, and the naturally infected ...
Apr 27, 2021
... noninvasive way, and she showed the feasibility to detect SIV infection in feces and urine. (8, 9, 10) She did it initially on experimentally infected chimpanzees, and the naturally infected ...
Apr 27, 2021
5.5 Andrew Rice — Mechanism of tat Transactivation
(HIV/AIDS Research: Its History & Future Meeting)
... showed that PTEFb activity or TAK activity is downregulated in resting CD4 T cells. (8) I'll get to that point in a few later slides. With the identity of the catalytic subunit of TAK ...
Apr 27, 2021
... showed that PTEFb activity or TAK activity is downregulated in resting CD4 T cells. (8) I'll get to that point in a few later slides. With the identity of the catalytic subunit of TAK ...
Apr 27, 2021
1.7 Max Essex — From Feline Leukemia Virus to AIDS in Africa
(HIV/AIDS Research: Its History & Future Meeting)
... didn't seem to cause as much disease or be as transmissible as did the feline leukemia virus. (8) Now, if we then move onto the period of human retroviruses. I was one of the people ...
Apr 27, 2021
... didn't seem to cause as much disease or be as transmissible as did the feline leukemia virus. (8) Now, if we then move onto the period of human retroviruses. I was one of the people ...
Apr 27, 2021
6.2 Dennis Burton — How Does HIV Evade the Antibody Response?
(HIV/AIDS Research: Its History & Future Meeting)
... got these antibodies, as I said, in these antibodies, we started to think about vaccines. (8) I apologize for this, pulling this whole abstract, but I really 00:08:00 ...
Apr 27, 2021
... got these antibodies, as I said, in these antibodies, we started to think about vaccines. (8) I apologize for this, pulling this whole abstract, but I really 00:08:00 ...
Apr 27, 2021
2.6 Tony Fauci — 35 Years of HIV/AIDS: Science and Policy
(HIV/AIDS Research: Its History & Future Meeting)
... laboratory at that time. As you can see on some of these papers, Bart is a coauthor with me. (8, 9, 10, 11, 12) He was a fellow in the lab before he left ...
May 25, 2021
... laboratory at that time. As you can see on some of these papers, Bart is a coauthor with me. (8, 9, 10, 11, 12) He was a fellow in the lab before he left ...
May 25, 2021
4.1 Ronald Desrosiers — The Origin of SIVmac: Non-human Primate Models for HIV
(HIV/AIDS Research: Its History & Future Meeting)
... published a report of the isolation of new type D virus associated with this immunodeficiency syndrome. (8) And indeed, this type D virus was the major cause of morbidity and mortality in our macaque ...
Apr 27, 2021
... published a report of the isolation of new type D virus associated with this immunodeficiency syndrome. (8) And indeed, this type D virus was the major cause of morbidity and mortality in our macaque ...
Apr 27, 2021
8.3 George Shaw — Transmitted/Founder HIV Genomes: What They Teach Us
(HIV/AIDS Research: Its History & Future Meeting)
... CTL recognition and escape, we decided we would try it for neutralizing antibodies. (8) People forget that in 2002 John Moore was writing review, after review, after ...
Apr 27, 2021
... CTL recognition and escape, we decided we would try it for neutralizing antibodies. (8) People forget that in 2002 John Moore was writing review, after review, after ...
Apr 27, 2021
3.5 Daria Hazuda: Discovery and Development of Integrase Inhibitors
(HIV/AIDS Research: Its History & Future Meeting)
... Human DNA Polymerases of 4′Ethynyl2Fluoro2′Deoxyadenosine.” Antimicrobial Agents and Chemotherapy 51, no. 8 (August 1, 2007): 2701–8. doi:10.1128/AAC.0027707 https://doi.org/10.1128/AAC.0027707. Index 1.5 John Coffin — The Origin ...
Apr 27, 2021
... Human DNA Polymerases of 4′Ethynyl2Fluoro2′Deoxyadenosine.” Antimicrobial Agents and Chemotherapy 51, no. 8 (August 1, 2007): 2701–8. doi:10.1128/AAC.0027707 https://doi.org/10.1128/AAC.0027707. Index 1.5 John Coffin — The Origin ...
Apr 27, 2021
5.6 Michael Emerman — Host-virus Co-evolution
(HIV/AIDS Research: Its History & Future Meeting)
... bit better, which calculated that HIV1 and SIV separated by 1,000 years ago. (8) Mike Worobey, who talked last night, did a really nice thing ...
Apr 27, 2021
... bit better, which calculated that HIV1 and SIV separated by 1,000 years ago. (8) Mike Worobey, who talked last night, did a really nice thing ...
Apr 27, 2021
2.2 James Curran — Deciphering the Epidemiology of AIDS
(HIV/AIDS Research: Its History & Future Meeting)
... believe, and Rich O’Reilly in New York, that this could be transmitted whatever it caused to infants. (8) The first documented heterosexual transmission came from New York with Carol A. Harris ...
Apr 27, 2021
... believe, and Rich O’Reilly in New York, that this could be transmitted whatever it caused to infants. (8) The first documented heterosexual transmission came from New York with Carol A. Harris ...
Apr 27, 2021
3.4 Raymond Schinazi — Discovery and Development of Novel NRTIs
(HIV/AIDS Research: Its History & Future Meeting)
... also to the people at Burroughs Wellcome. #reproducibility; experimental reproduction This is Cheng's paper on PNAS. (8) And Burroughs Wellcome scientists also discovered the activity of 3TC and FTC with the Emory group ...
Apr 27, 2021
... also to the people at Burroughs Wellcome. #reproducibility; experimental reproduction This is Cheng's paper on PNAS. (8) And Burroughs Wellcome scientists also discovered the activity of 3TC and FTC with the Emory group ...
Apr 27, 2021
2.5 Françoise Barré-Sinoussi — Discovery of HIV
(HIV/AIDS Research: Its History & Future Meeting)
... group, that CD4 00:17:00 molecule was indeed the main receptor for this virus. (8, 9) On this slide, I'm showing also what we could see in the culture ...
Apr 27, 2021
... group, that CD4 00:17:00 molecule was indeed the main receptor for this virus. (8, 9) On this slide, I'm showing also what we could see in the culture ...
Apr 27, 2021
6.3 Bruce Walker — Role of T Cells in Controlling HIV Infection
(HIV/AIDS Research: Its History & Future Meeting)
... reasons why this T cell response that should have been working, wasn't. (8) Nef was protecting cells from killing, by downregulating HLA Class 1. We ...
Apr 27, 2021
... reasons why this T cell response that should have been working, wasn't. (8) Nef was protecting cells from killing, by downregulating HLA Class 1. We ...
Apr 27, 2021
5.1 Flossie Wong-Staal — Discovery of Human Retroviral Transactivators
(HIV/AIDS Research: Its History & Future Meeting)
... WainHobson published their data 00:08:30 in Cell, also in January 1985. (8) Now, it's not just the scientists who are competing, the journals are still competing because ...
Apr 27, 2021
... WainHobson published their data 00:08:30 in Cell, also in January 1985. (8) Now, it's not just the scientists who are competing, the journals are still competing because ...
Apr 27, 2021
6.7 Salim Abdool Karim — Stopping the Spread of HIV in Developing Countries
(HIV/AIDS Research: Its History & Future Meeting)
... tools we have, we can have a huge impact on the HIV epidemic. (8) Yes, HIV epidemic control is achievable. However, we have to have a vaccine ...
Apr 27, 2021
... tools we have, we can have a huge impact on the HIV epidemic. (8) Yes, HIV epidemic control is achievable. However, we have to have a vaccine ...
Apr 27, 2021
5.3 Michael Malim — Discovery of APOBEC Restriction
(HIV/AIDS Research: Its History & Future Meeting)
... out that APOBEC3G fell in a family of 11 human genes, which are indicated here. (8) Now, two of them have been worked on a fair amount. Prior to that APOBEC1 ...
Apr 27, 2021
... out that APOBEC3G fell in a family of 11 human genes, which are indicated here. (8) Now, two of them have been worked on a fair amount. Prior to that APOBEC1 ...
Apr 27, 2021
2.4 Robert Gallo — Discoveries of Human Retrovirus, Their Linkage to Disease as Causative Agents & Preparation for the Future
(HIV/AIDS Research: Its History & Future Meeting)
... T cell growth factor or interleukin2 (IL2) by our group in 1976. (7, 8) I want to remind you that came up once earlier, that lymphocytes were ...
Apr 27, 2021
... T cell growth factor or interleukin2 (IL2) by our group in 1976. (7, 8) I want to remind you that came up once earlier, that lymphocytes were ...
Apr 27, 2021
1.5 John Coffin — The Origin of Molecular Retrovirology
(HIV/AIDS Research: Its History & Future Meeting)
... radionuclide, radiolabeling, radioactive tracer #journal publishing politics #memory It started with this one (8) which actually came from the Houston meeting, it 00:16:30 was somewhat ...
Apr 27, 2021
... radionuclide, radiolabeling, radioactive tracer #journal publishing politics #memory It started with this one (8) which actually came from the Houston meeting, it 00:16:30 was somewhat ...
Apr 27, 2021
3.2 Samuel Broder: The First Clinical Trials of Antiretroviral Drugs
(HIV/AIDS Research: Its History & Future Meeting)
... Here's an example. We published a paper early in 1987 to summarise some results. (8) Here's a normal glucose uptake metabolism of the brain on a 00:19:00 PET ...
Apr 27, 2021
... Here's an example. We published a paper early in 1987 to summarise some results. (8) Here's a normal glucose uptake metabolism of the brain on a 00:19:00 PET ...
Apr 27, 2021
6.1 Sharon Hillier — Development and Application of Pre-exposure Prophylaxis (PrEP)
(HIV/AIDS Research: Its History & Future Meeting)
... 2012–2016) team, and presented at CROI (Conference on Retroviruses and Opportunistic Infections) this year. (8) The first studies of tenofovir gel as a rectal microbicide this year. And we're beginning to see ...
Apr 27, 2021
... 2012–2016) team, and presented at CROI (Conference on Retroviruses and Opportunistic Infections) this year. (8) The first studies of tenofovir gel as a rectal microbicide this year. And we're beginning to see ...
Apr 27, 2021
6.6 Robert Redfield — The PEPFAR Program to Treat HIV in Africa
(HIV/AIDS Research: Its History & Future Meeting)
... 00:21:30 a reasonable period of time going forward. (6, 7, 8, 9) I have my miracle slide two. We should be more ...
Apr 27, 2021
... 00:21:30 a reasonable period of time going forward. (6, 7, 8, 9) I have my miracle slide two. We should be more ...
Apr 27, 2021
9.1 Jon Cohen — Responding to AIDS: A Journalist's View
(HIV/AIDS Research: Its History & Future Meeting)
... scientific press conference of all time, I believe, on April 23rd 1984. (8) 00:05:00 The day before it occurs, The New York Times runs ...
Apr 27, 2021
... scientific press conference of all time, I believe, on April 23rd 1984. (8) 00:05:00 The day before it occurs, The New York Times runs ...
Apr 27, 2021
Session 10: What Have We Learned?
(HIV/AIDS Research: Its History & Future Meeting)
... too. Jim: I’d like to be able to read a book is that I could from 8:00 at night to 10:00 then I’m finished. I’m a fast reader, but not too ...
Apr 27, 2021
... too. Jim: I’d like to be able to read a book is that I could from 8:00 at night to 10:00 then I’m finished. I’m a fast reader, but not too ...
Apr 27, 2021
9.3 Victoria Harden — The Future of the History of AIDS
(HIV/AIDS Research: Its History & Future Meeting)
... different perspectives are Randy Shilts' (1951–1994)early very moving account (8), Larry Kramer's (1935–2020) caustic stories (9), Abe Verghese's (b ...
Apr 27, 2021
... different perspectives are Randy Shilts' (1951–1994)early very moving account (8), Larry Kramer's (1935–2020) caustic stories (9), Abe Verghese's (b ...
Apr 27, 2021
6.5 Emilio Emini — Issues in HIV Vaccine Development: Will the Future be any Easier than the Past?
(HIV/AIDS Research: Its History & Future Meeting)
... George Shaw 00:10:30 down at UAB (University of Alabama at Birmingham). (8) This was a study in which—and Doug Richman mentioned this yesterday, where we showed—and this was in patients ...
Apr 27, 2021
... George Shaw 00:10:30 down at UAB (University of Alabama at Birmingham). (8) This was a study in which—and Doug Richman mentioned this yesterday, where we showed—and this was in patients ...
Apr 27, 2021
4.4 Michael Worobey — Spread of HIV in the New World
(HIV/AIDS Research: Its History & Future Meeting)
... five minutes to 10, but I'm going to force you to look at this phylogeny for a second. (8) Because if you can see: This is now HIV1 group M. Subtype B ...
Apr 27, 2021
... five minutes to 10, but I'm going to force you to look at this phylogeny for a second. (8) Because if you can see: This is now HIV1 group M. Subtype B ...
Apr 27, 2021
3.6 John C. Martin — Making it Simpler: A Single Pill to Treat HIV
(HIV/AIDS Research: Its History & Future Meeting)
... many people in this room, we were able to convince FDA to accept this design. (8) That is take patients who, according to guidelines are failing and should get three new ...
Apr 27, 2021
... many people in this room, we were able to convince FDA to accept this design. (8) That is take patients who, according to guidelines are failing and should get three new ...
Apr 27, 2021
4.3 Beatrice Hahn — Apes to Humans: The Origin of HIV
(HIV/AIDS Research: Its History & Future Meeting)
... human viruses and it was clear that there were, at that time at least, three different crossspecies transmissions. (8) And we proposed, as Martine had shown you, that bushmeat hunting is a risk behavior ...
Nov 11, 2021
... human viruses and it was clear that there were, at that time at least, three different crossspecies transmissions. (8) And we proposed, as Martine had shown you, that bushmeat hunting is a risk behavior ...
Nov 11, 2021
Session 7: Prospects for an HIV Vaccine
(HIV/AIDS Research: Its History & Future Meeting)
... mosaic HIV vaccine and formed a consortium of partners to do so. (6, 7, 8, 9, 10, 11, 12, 13, 14, 15) In the next few months ...
Apr 27, 2021
... mosaic HIV vaccine and formed a consortium of partners to do so. (6, 7, 8, 9, 10, 11, 12, 13, 14, 15) In the next few months ...
Apr 27, 2021