During a clinical trial, a surrogate marker or surrogate endpoint is an effect measured during the trial that is a substitute for the intended clinical outcome or clinical endpoint. This is an alternative to measuring the actual clinical outcome during the trial.
Found 5 search result(s) for surrogate.
clinical endpoint, clinical outcome
(HIV/AIDS Research: Its History & Future Meeting)
... clinical research) the "clinical endpoint" is the desired outcome of the treatment being tested. Contrast with surrogate marker (surrogate endpoint
Dec 31, 2020
... clinical research) the "clinical endpoint" is the desired outcome of the treatment being tested. Contrast with surrogate marker (surrogate endpoint
Dec 31, 2020
2.3 Mark Harrington — The Importance of Activism to the US Response
(HIV/AIDS Research: Its History & Future Meeting)
... year to really change the way that they regulate drugs to allow earlier approval based on surrogate markers, even what turned out to be shitty surrogate markers like CD4 cells and changes in CD4 cells from single nuc ...
Apr 27, 2021
... year to really change the way that they regulate drugs to allow earlier approval based on surrogate markers, even what turned out to be shitty surrogate markers like CD4 cells and changes in CD4 cells from single nuc ...
Apr 27, 2021
8.1 John Mellors — MACS and Beyond: Epidemiology, Viremia and Pathogenesis
(HIV/AIDS Research: Its History & Future Meeting)
... you about the first step as a prognostic biomarker. (8, 9) As important is to validate as a surrogate endpoint for treatment trials, meaning that a change in the marker is a surrogate for a clinical outcome 00:08:30 AIDS or death. This was nicely shown by two ...
Apr 27, 2021
... you about the first step as a prognostic biomarker. (8, 9) As important is to validate as a surrogate endpoint for treatment trials, meaning that a change in the marker is a surrogate for a clinical outcome 00:08:30 AIDS or death. This was nicely shown by two ...
Apr 27, 2021
3.3 Douglas Richman: Antiviral Drug Resistance and Combination ART
(HIV/AIDS Research: Its History & Future Meeting)
... 00:31:30 in a prospectively collected patient population clinical specimen, was a good surrogate marker for progression. I would hope that that would be included whatever record is created ...
Apr 27, 2021
... 00:31:30 in a prospectively collected patient population clinical specimen, was a good surrogate marker for progression. I would hope that that would be included whatever record is created ...
Apr 27, 2021
2.4 Robert Gallo — Discoveries of Human Retrovirus, Their Linkage to Disease as Causative Agents & Preparation for the Future
(HIV/AIDS Research: Its History & Future Meeting)
... Robin said last night as well. Making reverse transcriptase assays sensitive to be a surrogate for finding a retrovirus and to make 00:07:00 sure we could distinguish ...
Apr 27, 2021
... Robin said last night as well. Making reverse transcriptase assays sensitive to be a surrogate for finding a retrovirus and to make 00:07:00 sure we could distinguish ...
Apr 27, 2021