CCR5 is a receptor protein on the surface of white blood cells. In HIV infection, the HIV virion coat protein gp120 binds to the T cell glycoprotein CD4 and to CCR5, triggering the cell to absorb the HIV virion and thus becoming infected.
Found 15 search result(s) for CCR5.
CCR5-Δ32
(HIV/AIDS Research: Its History & Future Meeting)
... CCR5Δ32 ("Delta 32") is an allele of the human CCR5 gene, and individuals who are homozygous for CCR5Δ32 are resistant to HIV1 infection
Jan 31, 2021
... CCR5Δ32 ("Delta 32") is an allele of the human CCR5 gene, and individuals who are homozygous for CCR5Δ32 are resistant to HIV1 infection
Jan 31, 2021
CCR5 receptor antagonist
(HIV/AIDS Research: Its History & Future Meeting)
... CCR5 receptor antagonists are drugs that block the CCR5 receptor, which HIV uses to gain entry into CD4 T cells
Mar 07, 2021
... CCR5 receptor antagonists are drugs that block the CCR5 receptor, which HIV uses to gain entry into CD4 T cells
Mar 07, 2021
maraviroc (Selzentry, Celsentri)
(HIV/AIDS Research: Its History & Future Meeting)
... Maraviroc (sold as Selzentry in the US and Celsentri in the EU) is a CCR5 receptor antagonist, approved for use in 2007
Jan 11, 2021
... Maraviroc (sold as Selzentry in the US and Celsentri in the EU) is a CCR5 receptor antagonist, approved for use in 2007
Jan 11, 2021
G protein-coupled receptor (GPCR)
(HIV/AIDS Research: Its History & Future Meeting)
... GPCRs are a large family of cell surface receptors that includes CCR5 (CC chemokine receptor type 5
Jan 29, 2021
... GPCRs are a large family of cell surface receptors that includes CCR5 (CC chemokine receptor type 5
Jan 29, 2021
env
(HIV/AIDS Research: Its History & Future Meeting)
... cleaved into gp120 and gp41, making up the envelope spike complex that binds to CD4, CCR5, and CXCR4
Aug 18, 2020
... cleaved into gp120 and gp41, making up the envelope spike complex that binds to CD4, CCR5, and CXCR4
Aug 18, 2020
CXCR4 (chemokine receptor type 4)
(HIV/AIDS Research: Its History & Future Meeting)
... HIV infection, HIV starts to bind to CXCR4, in addition to the usual combination of CD4 and CCR5
Jan 03, 2021
... HIV infection, HIV starts to bind to CXCR4, in addition to the usual combination of CD4 and CCR5
Jan 03, 2021
5.4 Edward Berger — Discovery of HIV Co-receptors
(HIV/AIDS Research: Its History & Future Meeting)
... March 28th. Ghalib actually used that cDNA clone 00:19:00 for CCR5 and did the various kinds of assays that I showed you before, and bingo. We ...
Apr 27, 2021
... March 28th. Ghalib actually used that cDNA clone 00:19:00 for CCR5 and did the various kinds of assays that I showed you before, and bingo. We ...
Apr 27, 2021
Berlin patient, Timothy Ray Brown (1966–2020)
(HIV/AIDS Research: Its History & Future Meeting)
term "Berlin patient" has been applied to two anonymous HIVinfected people who were given experimental treatments in Berlin, Germany, and were subsequently determined to be free of HIV. The first "Berlin patient" was diagnosed with HIV infection in 1995, and given ...
Jan 31, 2021
term "Berlin patient" has been applied to two anonymous HIVinfected people who were given experimental treatments in Berlin, Germany, and were subsequently determined to be free of HIV. The first "Berlin patient" was diagnosed with HIV infection in 1995, and given ...
Jan 31, 2021
Genes
(HIV/AIDS Research: Its History & Future Meeting)
Note: genes are usually specified in italics, while their corresponding proteins are specified in roman. For example, the tat gene encodes the Tat or "TransActivator of Transcription" protein. Proteins are indexed under Tools, methods, materials, drugs, and treatments. All retroviruses have the genes ...
Mar 01, 2021
Note: genes are usually specified in italics, while their corresponding proteins are specified in roman. For example, the tat gene encodes the Tat or "TransActivator of Transcription" protein. Proteins are indexed under Tools, methods, materials, drugs, and treatments. All retroviruses have the genes ...
Mar 01, 2021
8.4 Robert Siliciano — The Challenge of the HIV Reservoir
(HIV/AIDS Research: Its History & Future Meeting)
... patients received an allogeneic stem cell transplant from donors who are wildtype for CCR5, and antiretroviral therapy was continued throughout the transplant period to prevent 00:16:00 ...
Apr 27, 2021
... patients received an allogeneic stem cell transplant from donors who are wildtype for CCR5, and antiretroviral therapy was continued throughout the transplant period to prevent 00:16:00 ...
Apr 27, 2021
3.5 Daria Hazuda: Discovery and Development of Integrase Inhibitors
(HIV/AIDS Research: Its History & Future Meeting)
... now had two new classes of oral agents to treat HIV infection: the CCR5 antagonists (maraviroc), which I relied on the brilliant work of Ed Berger that you'll ...
Apr 27, 2021
... now had two new classes of oral agents to treat HIV infection: the CCR5 antagonists (maraviroc), which I relied on the brilliant work of Ed Berger that you'll ...
Apr 27, 2021
5.1 Flossie Wong-Staal — Discovery of Human Retroviral Transactivators
(HIV/AIDS Research: Its History & Future Meeting)
... antibody. Likewise, you get virus rebound very, very early. Pro140 is a CCR5 antibody and that's doing much better. You see it but still, it doesn't persist ...
Apr 27, 2021
... antibody. Likewise, you get virus rebound very, very early. Pro140 is a CCR5 antibody and that's doing much better. You see it but still, it doesn't persist ...
Apr 27, 2021
2.4 Robert Gallo — Discoveries of Human Retrovirus, Their Linkage to Disease as Causative Agents & Preparation for the Future
(HIV/AIDS Research: Its History & Future Meeting)
... they're from CD4 cells as well. (20) These are the beta chemokines, the natural ligands for the CCR5, which is, as you know, a coreceptor. We, in no way, found the coreceptor this is chiefly, by far ...
Apr 27, 2021
... they're from CD4 cells as well. (20) These are the beta chemokines, the natural ligands for the CCR5, which is, as you know, a coreceptor. We, in no way, found the coreceptor this is chiefly, by far ...
Apr 27, 2021
1.4 Robin Weiss — Retrovirus History and Early Searches for Human Retroviruses
(HIV/AIDS Research: Its History & Future Meeting)
... doi:10.1016/00928674(86)905908 https://doi.org/10.1016/00928674(86)905908. Identification of CXCR4 and CCR5: Feng, Yu, Christopher C. Broder, Paul E. Kennedy, and Edward A. Berger ...
Apr 27, 2021
... doi:10.1016/00928674(86)905908 https://doi.org/10.1016/00928674(86)905908. Identification of CXCR4 and CCR5: Feng, Yu, Christopher C. Broder, Paul E. Kennedy, and Edward A. Berger ...
Apr 27, 2021
2.6 Tony Fauci — 35 Years of HIV/AIDS: Science and Policy
(HIV/AIDS Research: Its History & Future Meeting)
... S. Fauci. “MacrophageTropic HIV and SIV Envelope Proteins Induce a Signal through the CCR5 Chemokine Receptor.” Nature 389, no. 6654 (October 30, 1997): 981–85 ...
May 25, 2021
... S. Fauci. “MacrophageTropic HIV and SIV Envelope Proteins Induce a Signal through the CCR5 Chemokine Receptor.” Nature 389, no. 6654 (October 30, 1997): 981–85 ...
May 25, 2021