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Chloramphenicol acetyltransferase (CAT) is an enzyme that disables the antibiotic compound chloramphenicol. The CAT gene can be used to test the the transcriptional activity in recombinant cloned viruses.

See Joseph G. Sodroski, Craig A. Rosen, and William A. Haseltine, “Trans-Acting Transcriptional Activation of the Long Terminal Repeat of Human T Lymphotropic Viruses in Infected Cells,” Science 225, no. 4660 (July 27, 1984): 381–85, doi:10.1126/science.6330891.

Found 1 search result(s) for Chloramphenicol.

Page: 5.1 Flossie Wong-Staal — Discovery of Human Retroviral Transactivators (HIV/AIDS Research: Its History & Future Meeting)
... motivation to do as much as we can, as fast as we can. #CAT assay (chloramphenicol acetyltransferase) In fact, I think in the first four years, I would say ...
Apr 27, 2021

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